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Detection of hepatitis C virus infection by enzyme-linked immunosorbent assay system using core protein expressed in
K Muraiso1, M Hijikata, N Kato
1Virology Division, National Cancer Center Research Institute, Tokyo.
Japanese Journal of Cancer Research : Gann
|August 1, 1991
Abstract:
Enzyme-linked immunosorbent assay of the core protein of hepatitis C virus (HCV) expressed in E. coli led to detection of the antibody against this virus in patients with chronic hepatitis. Some of the negative results obtained using a different viral protein became positive with this E. coli-expressed viral protein, and were also positive for the viral RNA. Thus, use of the core protein of HCV facilitates accurate detection of HCV infection.