Related Experiment Video
Updated: Jul 18, 2026

05:57
In Vitro Assay of Bacterial Adhesion onto Mammalian Epithelial Cells
Published on: May 16, 2011
Identification of a Moraxella catarrhalis gene that confers adherence to various human epithelial cell lines in vitro
Serena L Lipski1, Melissa M Holm, Eric R Lafontaine
1Department of Medical Microbiology and Immunology, Medical University of Ohio, Toledo, OH 43614, USA.
FEMS Microbiology Letters
|December 15, 2006
Abstract:
Moraxella catarrhalis is a pathogen of the human airways. We found that expression of the M. catarrhalis gene mcmA by Escherichia coli increases adherence to epithelial cells 100-fold. Furthermore, we discovered that disrupting mcmA decreases M. catarrhalis adherence to laryngeal and lung cells, which are relevant to pathogenesis by the bacterium.

