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Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma
Published on: March 30, 2018
Follicular lymphoma presenting as mumps, with persistent cervical lymphadenopathy.
A S Cole1, M I Trotter, J O'Connell
1Department of Otolaryngology, City Hospital Birmingham, Birmingham, UK. aadamcole@aol.com
The Journal of Laryngology and Otology
|December 15, 2006
Summary
Follicular lymphoma can mimic mumps in healthy individuals. Persistent lymphadenopathy after mumps diagnosis warrants further investigation for underlying conditions like lymphoma.
Area of Science:
- Oncology
- Infectious Diseases
- Pathology
Background:
- Follicular lymphoma is a type of non-Hodgkin lymphoma.
- Mumps is a viral infection typically causing swelling of salivary glands.
- Differential diagnosis of lymphadenopathy can be challenging.
Observation:
- A healthy individual presented with symptoms consistent with mumps, including sore throat and lymphadenopathy.
- Initial fine needle aspiration did not detect malignant cells.
- Persistent lymphadenopathy led to an excision biopsy.
Findings:
- The patient was diagnosed with follicular lymphoma.
- This represents the first reported case of follicular lymphoma presenting with mumps-like symptoms.
- The diagnosis was confirmed via excision biopsy of a lymph node.
Implications:
- This case underscores the importance of thorough follow-up for persistent lymphadenopathy, even after a presumed diagnosis of mumps.
- It highlights the need to consider uncommon presentations of follicular lymphoma.
- Clinicians should maintain a high index of suspicion for underlying malignancies in cases of prolonged or atypical lymphadenopathy.
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