Related Experiment Video
Updated: Jul 18, 2026

08:32
Assessment of Intestinal Transcytosis of Neonatal Escherichia coli Bacteremia Isolates
Published on: February 17, 2023
Intractable Bacillus cereus bacteremia in a preterm neonate
Anna B John1, Eissa A S A Razak, Emad E M H Razak
1Department of Pediatrics, Al-Adan Hospital, Hadiya, Kuwait.
Journal of Tropical Pediatrics
|December 15, 2006
Summary
Bacillus cereus can cause serious infections, even in newborns. This study details a preterm infant
Area of Science:
- Neonatal Medicine
- Infectious Diseases
- Microbiology
Background:
- Bacillus species, commonly seen as contaminants, are increasingly recognized in severe systemic infections.
- While rare, Bacillus cereus bacteremia poses a significant risk, particularly in vulnerable populations like preterm neonates.
Observation:
- A case of early-onset Bacillus cereus bacteremia in a preterm neonate is presented.
- The neonate exhibited clinical signs consistent with systemic infection.
Findings:
- The preterm neonate was successfully treated with vancomycin.
- This highlights the efficacy of vancomycin in managing Bacillus cereus bacteremia in neonates.
Implications:
- Clinicians should consider Bacillus species in the differential diagnosis of neonatal infections, even if rare.
- Prompt diagnosis and appropriate antibiotic therapy, such as vancomycin, are crucial for favorable outcomes in neonatal Bacillus cereus infections.
Related Concept Videos
Bacterial Meningitis I: Introduction
Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...
Bacterial Meningitis
Bacterial meningitis is a severe infectious disease involving inflammation of the meninges, the protective membranes surrounding the brain and spinal cord. It occurs when pathogenic bacteria cross the blood–brain barrier and enter the cerebrospinal fluid. Common causative organisms include Neisseria meningitidis, Streptococcus pneumoniae, Haemophilus influenzae type b, Listeria monocytogenes, and Escherichia coli K1. The exact route of entry varies by pathogen and host condition.Routes of Entry...
Bacterial Gastroenteritis
Bacterial gastroenteritis, characterized by diarrhea, abdominal cramps, and vomiting, is often caused by ingestion of contaminated food or water and is frequently associated with pathogenic Escherichia coli strains. These microbes exploit two principal mechanisms to inflict disease.Shiga toxin–producing E. coli, also referred to as STEC—notably O157:H7—release Shiga toxins that target ribosomes, blocking protein synthesis. The B subunit of the toxin binds the host glycolipid receptor...
Bacterial Meningitis II: Pathophysiology
Bacterial meningitis typically begins when pathogens such as Neisseria meningitidis and Streptococcus pneumoniae colonize the nasopharynx and invade the bloodstream. This process is facilitated by bacterial virulence factors, such as polysaccharide capsules, which resist phagocytosis and complement-mediated killing. Less commonly, bacteria reach the central nervous system via contiguous spread from infections like otitis media or sinusitis, through congenital or acquired dural defects, or...
Botulism
Botulism is a life-threatening neuroparalytic condition caused by botulinum neurotoxin, which is produced by the bacterium Clostridium botulinum, a Gram-positive, spore-forming, obligate anaerobe.In adults, the toxin enters the body in different ways: in foodborne botulism, the preformed toxin is absorbed in the intestine. In wound botulism, spores grow in injured tissue and release the toxin into the blood. Infant botulism differs mechanistically from adult forms. In infants, botulism commonly...
Brain Abscess l: Introduction
A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial infections,...

