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Updated: Jul 18, 2026

A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
Cutaneous melanoma with tonsillar metastasis.
Emilios E Pakos1, Pericles G Tsekeris, Penelope V Gogou
1Department of Radiation Therapy, University Hospital of Ioannina, University of Ioannina School of Medicine, Ioannina, Greece. epakos@yahoo.gr
Metastases to the tonsil are rare, especially from cutaneous melanoma. This case highlights a late-stage hematogenous spread to the tonsillar fossa, indicating advanced disease.
Area of Science:
- Oncology
- Pathology
Background:
- Hematogenous dissemination is a rare cause of tonsillar fossa metastases.
- Cutaneous melanoma can metastasize distantly, even years after initial treatment.
Observation:
- A case of cutaneous melanoma with a metastasis to the tonsil is presented.
- The metastasis occurred approximately 4 years after the primary diagnosis.
Findings:
- The tonsillar metastasis was presumed to be due to hematogenous spread.
- The patient's primary disease was treated with palliative radiation therapy.
Implications:
- This case underscores the potential for late and unusual metastatic patterns in cutaneous melanoma.
- Recognizing rare metastatic sites is crucial for accurate staging and prognosis in advanced cancers.
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