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Unexpectedly high toxicity of MACOP-B in young patients with low grade lymphoma
R Arranz1, G Pérez, J L Steegmann
1Servicio de Hematologia, Hospital de la Princesa, Madrid, Spain.
American Journal of Hematology
|September 1, 1991
Abstract:
We report the results of treatment with MACOP-B in 11 young patients with low grade lymphoma (LGL). Complete remission was obtained in 4 (57%) and partial remission in 3 (42.8%) of 7 evaluable patients. However, this aggressive chemotherapy has not offered any advantage because of an unacceptably high treatment-related morbidity and mortality (17%). Serious infection during neutropenia was the most common complication.