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[Comparative study of immunosuppressive properties of pregnancy- associated protein A, alpha 2-glucoprotein and alpha
Effects of high-molecular proteinase inhibitors on spontaneous and mitogen-induced lymphocyte proliferation were examined in males and pregnant and non-pregnant females. All three proteins, A protein, alpha 2-glycoprotein, and alpha 2-macroglobulin were found to be potent immunosuppressors and their activity was determined by the stage of pregnancy, the dose and mode of mitogenic lymphocyte stimulation.
Effects of high-molecular proteinase inhibitors on spontaneous and mitogen-induced lymphocyte proliferation were examined in males and pregnant and non-pregnant females. All three proteins, A protein, alpha 2-glycoprotein, and alpha 2-macroglobulin were found to be potent immunosuppressors and their activity was determined by the stage of pregnancy, the dose and mode of mitogenic lymphocyte stimulation.