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A novel micronutrient supplement in skin aging: a randomized placebo-controlled double-blind study

Alain Béguin1

  • 1Skin Testing Department, Intercosmetica Neuchâtel SA, Neuchâtel, Switzerland. alain.beguin@intercosmetica.ch

Journal of Cosmetic Dermatology
|December 16, 2006
PubMed
Abstract

Insights

A novel micronutrient supplement (Estime) significantly improved skin aging signs like wrinkles and skin appearance in a 4-month study. This oral supplement demonstrated safety and efficacy in protecting and repairing skin, with lasting benefits observed.

Area of Science:

  • Dermatology and Nutritional Science
  • Skin Health and Aging Research

Background:

  • Skin aging results from intrinsic factors and environmental damage, primarily UV radiation.
  • This process leads to collagen degradation, fine lines, and wrinkles.

Purpose of the Study:

  • To evaluate the efficacy and safety of a new oral micronutrient supplement, Estime, for mitigating skin aging.
  • To assess the supplement's impact on skin structure and appearance.

Main Methods:

  • A 4-month randomized, double-blind, placebo-controlled study involving 40 participants.
  • Efficacy was measured through skin surface evaluation, ultrasound imaging of dermal density, and photographic analysis over 3 months of supplementation and a 1-month follow-up.

Main Results:

  • The Estime group showed continuous and significant improvements in all measured skin parameters compared to placebo.
  • Visible enhancements in overall skin appearance and reduction in fine lines were noted.
  • Ultrasound revealed up to a 78% increase in dermal density (P < 0.0001) in the active group.

Conclusions:

  • Estime is an effective and safe oral supplement for skin protection and repair, combating signs of aging.
  • Further research is recommended to explore its long-term benefits and applications.

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