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Published on: July 25, 2017
Intraoperative cytology of clear cell carcinoma of the ovary
D Vrdoljak-Mozetic1, T Stanković, M Krasević
1Department of Gynecological Cytology, Unviersity Department of Gynecology and Obstetrics, University Hospital Center Rijeka, Rijeka, Croatia. danijela.vrdoljak-mozetic@ri.htnet.hr
Objective:
To describe the cytomorphology of clear cell carcinoma (CCC) of the ovary in intraoperative samples of peritoneal fluid, imprint and scraping samples of the tumour tissue.
Study Design:
Fourteen histologically confirmed cases, stained by standard cytological procedures, were analysed by light microscopy.
Results:
In 33.3% of peritoneal fluid samples and 92.9% of imprint and scraping cytological samples, besides variable clear cell cellular morphology, one or both distinct cytological characteristics were observed: eosinophilic, hyaline, extracellular, globular substance with or without formation of a 'raspberry' body and an eosinophilic, intracytoplasmic inclusions. These structures were clearly seen only in samples stained by May-Grünwald-Giemsa.
Conclusion:
Using cytological analysis of imprint and scraping samples of ovarian tumours it is possible to make a precise intraoperative cytological diagnosis in most cases of CCC of the ovary.
