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Updated: Jul 18, 2026

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Published on: August 28, 2020
Detrusor-sphincter dyssynergia
D Castro-Diaz1, J M Taracena Lafuente
1Department of Urology, University Hospital of the Canary Islands Ofra, La Laguna, Santa Cruz de Tenerife, Spain. davidcastro@teide.net
Detrusor-sphincter dyssynergia disrupts normal bladder function due to neurological issues. This condition requires effective treatment to prevent severe complications in affected individuals.
Area of Science:
- Neuroscience
- Urology
Background:
- Micturition is controlled by complex neurological pathways involving neurotransmitters.
- Normal bladder function requires coordinated detrusor muscle contraction and external urethral sphincter relaxation.
Purpose of the Study:
- To review the neurological control of micturition.
- To discuss detrusor-sphincter dyssynergia and its complications.
- To explore current and potential therapeutic approaches.
Main Methods:
- Literature review of neurological control of micturition.
- Analysis of the pathophysiology of detrusor-sphincter dyssynergia.
- Overview of existing and emerging treatment modalities.
Main Results:
- Detrusor-sphincter dyssynergia results from a loss of coordinated bladder and sphincter function.
- Neurological diseases can cause this condition by distorting neural control of the lower urinary tract.
- Over 50% of affected men may face severe complications without adequate treatment.
Conclusions:
- Finding curative treatments for detrusor-sphincter dyssynergia is challenging due to its complex neurological basis.
- Current therapies offer partial or temporary relief.
- Some treatment modalities show promising future potential.
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