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Updated: Jan 11, 2026

In Vivo Visualization of Calcium Transients during Fertilization and Early Development in C. elegans
Published on: July 12, 2024
Conductance rise induced by the calcium ionophore A23187 in unfertilized eggs of tilapia
1Laboratoire de Physiologie Cellulaire et Comparée, Faculté des Sciences, Université de Nice, Sophia Antipolis, France.
Abstract:
Current-clamp measurements on unfertilized tilapia eggs gave linear current-voltage relations in the range 0 to -120 mV. Eggs had low resting potentials (-22 mV) and high specific membrane resistances (500 k omega cm2) and specific membrane capacitances (0.9 microF cm-2) indicating no marked folding of their plasma membrane. Application of A23187 induced a small depolarization and a conductance rise, the response having a reversal potential of about -16 mV. The results suggest that tilapia eggs have a calcium-gated conductance probably activated at fertilization.
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