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Updated: Jul 18, 2026

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
Evolving medical knowledge: moving toward efficiently answering questions and keeping current
1Department of Family Medicine, The Ohio State University College of Medicine, OSU Family Practice at Upper Arlington, 1615 Fishinger Road, Columbus, OH 43221, USA. john.mcconaghy@osumc.edu
Abstract:
The information needs of clinicians are many and varied; however, these information needs remain largely unmet. This likely diminishes the quality of patient care. Although it is important that physicians be proficient in critically evaluating the medical literature, it is more important that they become proficient in the "applied science of information management." Clinicians must learn the techniques and skills to find, evaluate, and use relevant and valid information both in the care of patients and in their careers of lifelong learning. Clinicians need sources for rapid retrieval of valid information at the point of care.
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