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Updated: Jul 18, 2026

Glioblastoma Relapse Post-Resection Model for Therapeutic Hydrogel Investigations
Published on: February 24, 2023
Patient with resected anaplastic astrocytoma and an image suggestive of relapse
S Maciá Escalante1, A Rodríguez Lescure, J M Segura Ibáñez
1Servicio de Oncología Médica, Hospital General Universitario de Elche, Elche, Alicante, Spain. smacia@tiscali.es
Abstract:
The main treatment of asctrocytomas is surgery, which serves a double purpose: diagnosis and treatment. Surgery can be complemented with radiotherapy. With respect to chemotherapy, there continues to be a controversy as to whether it has the capacity to overcome the blood-brain barrier. An interesting option has been the implantation of biodegradable polymers of carmustine that are placed in the cavity left by the surgical procedure. With respect to the cerebral edema that can be associated with the carmustine implants, there can appear images in follow-up that are suggestive of relapse.

