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Updated: Jul 18, 2026

Generation and Grafting of Tissue-engineered Vessels in a Mouse Model
Published on: March 18, 2015
Vascular grafts and the endothelium
Michel R Hoenig1, Gordon R Campbell, Julie H Campbell
1Centre for Research in Vascular Biology, Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Brisbane, Australia.
Abstract:
This article discusses the importance of the endothelium for successful vascular grafts derived from both native arteries and synthetic materials. It also discusses the fundamental strategies to endothelialize synthetic grafts in animal experiments and in the clinic, as well as the use of endothelial progenitor cells (EPCs), bone marrow-derived cells, and mesothelium as endothelial substitutes.
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