Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Prenatal diagnosis of structural abnormalities.

R C Sanders1

  • 1Ultrasound Institute of Baltimore, Maryland.

Current Opinion in Obstetrics & Gynecology
|April 1, 1991
PubMed
Summary

Improved ultrasound and maternal blood tests offer effective screening for Down's syndrome and spina bifida. Further invasive testing like amniocentesis may be considered based on these noninvasive results.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Operative Surgery in the Azamgarh Sudder Dispensary.

The Indian medical gazette·2017
Same author

Liver Abscess Treated by Aspiration.

The Indian medical gazette·2017
Same author

To Remove In-Growing Toe Nail.

The Indian medical gazette·2017
Same author

Case of Floating Cartaract: Extraction.

The Indian medical gazette·2017
Same author

A Case of Acute Tonsilitis Accompanied with Suppuration of the Parotid Gland.

The Indian medical gazette·2017
Same author

Case of Ovariotomy: Successful Result.

The Indian medical gazette·2017

Area of Science:

  • Medical Imaging
  • Prenatal Diagnosis
  • Genetics

Background:

  • Recent advancements in ultrasound technology enhance the detection of subtle fetal anomalies.
  • Screening for common conditions like Down's syndrome and spina bifida is a key area of prenatal care.

Purpose of the Study:

  • To review the efficacy of combined ultrasonographic and maternal serum screening for common fetal anomalies.
  • To discuss the necessity of amniocentesis in conjunction with noninvasive screening methods.
  • To explore ultrasonographic markers associated with trisomy syndromes and renal abnormalities linked to chromosomal defects.

Main Methods:

  • Review of current literature and diagnostic guidelines.
  • Analysis of combined screening protocols utilizing ultrasound and maternal serum markers (e.g., alpha-fetoprotein).
  • Examination of ultrasonographic markers for chromosomal abnormalities and associated conditions.

Main Results:

  • Improved ultrasound quality increases the detection rate of subtle fetal abnormalities.
  • Combined screening approaches show promise for detecting conditions like Down's syndrome and spina bifida.
  • Specific ultrasonographic markers are associated with trisomy syndromes and renal defects.

Conclusions:

  • Noninvasive screening methods, including advanced ultrasound and maternal blood tests, are becoming more effective.
  • The decision to proceed with amniocentesis should be guided by combined screening results and risk assessment.
  • Further research into ultrasonographic markers can improve the diagnosis of chromosomal and renal abnormalities.

Related Experiment Videos