Related Experiment Videos
Total gastrectomy for advanced cancer. A worthwhile palliative procedure.
J R Monson1, J H Donohue, D C McIlrath
1Department of Surgery, Mayo Clinic, Rochester, Minnesota 55905.
Cancer
|November 1, 1991
Summary
Total gastrectomy (TG) offers a worthwhile palliative option for selected advanced gastric cancer patients. This procedure can prolong good quality of life with acceptable morbidity and mortality rates.
Area of Science:
- Surgical Oncology
- Gastroenterology
Background:
- Subtotal gastric resection is standard for advanced gastric cancer palliation.
- The role of total gastrectomy (TG) in advanced gastric adenocarcinoma remains debated.
Purpose of the Study:
- To evaluate the outcomes and quality of life after total gastrectomy (TG) for advanced gastric adenocarcinoma.
Main Methods:
- Retrospective review of 53 consecutive patients undergoing TG for advanced gastric adenocarcinoma between 1980 and 1989.
- Analysis of indications, postoperative complications, survival, and quality of life.
Main Results:
- Indications for TG were tumor location (30%) and extent (70%), including linitis plastica (17%).
- Postoperative mortality was 8%, with 11% requiring reoperation.
- Median survival was 19 months; 24% survived over 2 years.
- Good, satisfactory, and poor quality of life was reported by 59%, 28%, and 13% of survivors, respectively.
Conclusions:
- Total gastrectomy (TG) is a beneficial procedure for carefully selected patients with advanced gastric adenocarcinoma.
- TG can achieve prolonged survival with an acceptable quality of life, low morbidity, and mortality.