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Gastrointestinal stromal tumours: experience with multislice CT
C De Leo1, M Memeo, F Spinelli
1Di.M.I.M.P., Sezione di Diagnostica per Immagini, Policlinico Universitario, Piazza Giulio Cesare 11, I-70124, Bari, Italy. catydeleo@libero.it
La Radiologia Medica
|December 16, 2006
Summary
Multislice computed tomography (MSCT) effectively identifies and characterizes gastrointestinal stromal tumors (GISTs). This imaging technique aids in detecting GISTs, defining their extent, and searching for metastases.
Area of Science:
- Radiology
- Gastroenterology
- Oncology
Background:
- Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal neoplasms of the gastrointestinal tract.
- Accurate diagnosis and characterization are crucial for patient management.
Purpose of the Study:
- To evaluate the utility of multislice computed tomography (MSCT) in identifying and characterizing GISTs.
- To assess MSCT's capability in determining tumor location, growth patterns, and metastatic spread.
Main Methods:
- Analysis of MSCT images from 27 patients with GIST.
- Scans performed pre- and post-contrast administration with bowel distension techniques.
- Evaluation of tumor presence, site, origin, growth pattern, density, adjacent structures, lymph nodes, and metastases.
Main Results:
- GISTs most commonly found in the stomach (18/27) and small bowel (7/27).
- Tumor sizes ranged from 1.5 cm to 21 cm, with extramucosal origin confirmed in 23/27 cases.
- Hepatic metastases detected in 5/27 patients; lymphadenomegaly in one case.
Conclusions:
- MSCT is an essential tool for diagnosing GISTs.
- It enables detection, defines tumor relationships, and aids in the search for metastases.
- MSCT plays a vital role in the pre-operative assessment and staging of GISTs.