Related Experiment Video
Updated: Jul 18, 2026

A Retrograde Implantation Approach for Peritoneal Dialysis Catheter Placement in Mice
Published on: July 20, 2022
[From CANUSA to ADEMEX: do we need a new paradigm for definition of peritoneal dialysis adequacy?]
1Unità Operativa di Nefrologia Dialisi e Trapianto Renale e CNR-IBIM, Istituto di Biomedicina, Azienda Ospedaliera, Reggio Calabria. eniag@libero.it
Abstract:
Peritoneal dialysis doses were prescribed out of empirical criteria up to the mid-Ninety Then, the observational CANUSA study and the experimental ADEMEX study helped to define adequacy criteria according to urea kinetics model. This review analyzes the limits of a definition of adequacy grounded exclusively on urea kinetics, as well as the need for new parameters of adequacy. The evidence is presented fostering the hypothesis that the control of extra-cellular fluid excess and of other cardiovascular risk factors may now be considered a new target for adequacy.
Related Concept Videos
Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications
Peritoneal Dialysis I: Introduction and Procedure
Hemodialysis I: Introduction
Peritoneal Dialysis III: Nursing Management
Hemodialysis II: Procedure and Complications
Dialysis
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...

