Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Hyperemic reactivity scintigraphy in endothelial function].

M Del Val Gómez1, M A San Martín, F G Gallardo

  • 1Servicios de Medicina Nuclear, Hospital Carlos III, Madrid.

Revista Espanola De Medicina Nuclear
|December 19, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Yield of xenodiagnosis and PCR in the evaluation of specific chemotherapy of Chagas' disease in children].

Boletin chileno de parasitologia·1998
Same author

[Percutaneous suprapubic bladder lithotripsy].

Annales d'urologie·1998
Same author

Factors associated with outcome in major depression: a 6-month prospective study.

Social psychiatry and psychiatric epidemiology·1998
Same author

[Simultaneous transplantation of fetal mesencephalic cells to the striatum and globus pallidus of rats with lesions induced by 6-hydroxydopamine].

Revista de neurologia·1998
Same author

Signs of glaucoma in rhesus monkeys from a restricted gene pool.

Journal of glaucoma·1998
Same author

The Bcl-2 gene is differentially regulated by IL-2 and IL-4: role of the transcription factor NF-AT.

Oncogene·1998

Hyperemic reactivity scintigraphy (HRS) correlates with flow-mediated dilatation (FMD) and can identify perfusion defects in myocardial SPECT scans. HRS may offer additional value in assessing cardiac health.

Area of Science:

  • Cardiovascular imaging
  • Nuclear cardiology
  • Vascular function assessment

Background:

  • Endothelial dysfunction is a key factor in cardiovascular disease.
  • Assessing endothelial function is crucial for cardiovascular risk stratification.
  • Current methods like flow-mediated dilatation (FMD) have limitations.

Purpose of the Study:

  • To compare hyperemic reactivity scintigraphy (HRS) with brachial artery FMD.
  • To evaluate the relationship between HRS, FMD, and myocardial SPECT findings.
  • To determine the clinical utility of HRS in patients undergoing myocardial scintigraphy.

Main Methods:

  • 42 patients undergoing myocardial scintigraphy were included; 36 had simultaneous FMD measurements.
  • HRS involved dynamic imaging post-Tc-99 sestamibi injection after upper arm occlusion.

Related Experiment Videos

  • Key HRS indices (MHA/MCA, MxHA/CxHA) were derived from time-activity curves.

    • Main Results:

    • A correlation was found between FMD and HRS indices (MHA/MCA, MxHA/CxHA).
    • Patients with myocardial perfusion defects showed lower MxHA/CxHA compared to those with normal SPECT.
    • No direct relationship was observed between FMD and SPECT-detected perfusion alterations.

    Conclusions:

    • Hyperemic reactivity scintigraphy (HRS) demonstrates a relationship with flow-mediated dilatation (FMD).
    • HRS can detect differences in patients with myocardial perfusion defects.
    • HRS may provide supplementary diagnostic information to standard myocardial scintigraphy.