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Updated: Jul 18, 2026

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Isolating Lymphocytes from the Mouse Small Intestinal Immune System
Published on: February 28, 2018
The lymphopenic mouse in immunology: from patron to pariah
Nevil J Singh1, Ronald H Schwartz
1Laboratory of Cellular and Molecular Immunology, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, 4 / 111 Center Drive, MSC-0420, Bethesda, Maryland 20892, USA.
Immunity
|December 19, 2006
Abstract:
A recent surge of interest in the behavior of T and B cells in lymphopenic model systems has resurrected a certain cynicism about the validity of using such models to answer important immunological questions. Here we discuss this skepticism in a broader historical context.

