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CD molecules 2006--human cell differentiation molecules

Heddy Zola1, Bernadette Swart, Alison Banham

  • 1Child Health Research Institute and Adelaide University Discipline of Paediatrics, 72 King William Road, North Adelaide, South Australia 5006, Australia. heddy.zola@adelaide.edu.au

Journal of Immunological Methods
|December 19, 2006
PubMed

Insights

The Human Leucocyte Differentiation Antigens Workshops, now Human Cell Differentiation Molecules, updated the CD nomenclature for cell surface molecules. This report summarizes new and revised CD designations approved in May 2006.

Area of Science:

  • Immunology
  • Cell Biology

Background:

  • The Human Leucocyte Differentiation Antigens Workshops (HLDA) have historically focused on characterizing leucocyte surface molecules and their antibodies since 1984.
  • The HLDA established the internationally recognized CD nomenclature, sanctioned by the International Union of Immunological Societies (IUIS).

Framework:

  • In 2004, the HLDA Council expanded its objectives and was renamed Human Cell Differentiation Molecules (HCDM).
  • This rebranding reflects a broader scope beyond just leucocytes to encompass human cell differentiation.

Implementation:

  • Workshop studies were conducted under the HCDM initiative in 2005 and early 2006.
  • A key meeting in May 2006 served as the platform for the Nomenclature Committee to review and approve updates.

Implications:

  • The meeting resulted in the approval of several new CD designations.
  • Existing CD designations were also modified, with all changes summarized in this report for researchers.
  • These updates ensure the continued accuracy and relevance of cell surface molecule classification.

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