Severe anaphylaxis to Gelofusine during a transthoracic echo bubble study

Area of Science:

• Anesthesiology
• Cardiology
• Pharmacology

Background:

• Transthoracic echocardiography is a common diagnostic procedure.
• Gelofusin is a widely used plasma volume expander.
• Patients with prior cerebral events may have unique risk factors.

Observation:

• A middle-aged woman experienced a severe anaphylactic reaction.
• The reaction occurred during a transthoracic echocardiogram.
• Gelofusin was administered as part of the procedure.

Findings:

• The case highlights a severe anaphylactic reaction to Gelofusin.
• This event occurred in a patient with a history of a cerebral event.
• The reaction necessitates careful consideration of Gelofusin use in at-risk populations.

Implications:

• Clinicians should be vigilant for anaphylaxis during echocardiography.
• Consideration of alternative agents may be warranted in patients with prior cerebral events.
• This case underscores the importance of monitoring for adverse drug reactions.