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Updated: Jul 18, 2026

Quantitation of Protein Expression and Co-localization Using Multiplexed Immuno-histochemical Staining and Multispectral Imaging
Published on: April 8, 2016
[Problems of structural and functional identification of biological tissues]
Abstract:
The theoretical methods of identification of topological and functional parameters for biological tissues, such as myocardium, are considered. Among the unknown topological parameters are the dimension and connectivity of a network, and the unknown functional parameters include the electrical resistance of the cellular membrane and cytoplasm. Experimentally known data are the sizes of cells (length and diameter), the input resistance of tissue, and also the field of electrical potential formed by a "dot" current source (by an intracellular microelectrode).
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