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Updated: Jul 18, 2026

Implantation and Monitoring by PET/CT of an Orthotopic Model of Human Pleural Mesothelioma in Athymic Mice
Published on: December 21, 2019
Dramatic tumour response to pemetrexed single-agent in an elderly patient with malignant peritoneal mesothelioma: a
Gianpiero Fasola1, Fabio Puglisi, Alessandro Follador
1Dept. of Medical Oncology, University Hospital, P.le S. M. Misericordia, 33100 Udine, Italy. fasola.gianpiero@aoud.sanita.fvg.it
Background:
To date, there is no standard treatment for unresectable malignant peritoneal mesothelioma; either best supportive care or systemic chemotherapy with palliative intent are accepted options.
Case Presentation:
Here, we report the case of a 79-year old patient with malignant peritoneal mesothelioma who was treated with pemetrexed single-agent and obtained an impressive long-lasting response.
Conclusion:
Single-agent pemetrexed is a treatment option for malignant peritoneal mesothelioma in selected elderly patients or in patients with unpaired performance status.
