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Updated: Jul 18, 2026
08:23
Culture Methods to Determine the Limit of Detection and Survival in Transport Media of Campylobacter Jejuni in Human Fecal Specimens
Published on: March 10, 2020
Campylobacter jejuni multilocus sequence types in humans, northwest England, 2003-2004
Will Sopwith1, Andrew Birtles, Margaret Matthews
1Health Protection Agency (North West), Liverpool, United Kingdom. will.sopwith@hpa.org.uk
Emerging Infectious Diseases
|December 21, 2006
Summary
Multilocus sequence typing (MLST) helps understand Campylobacter epidemiology by differentiating strains. This study shows MLST can reveal variations in campylobacteriosis across different populations.
Area of Science:
- Microbiology
- Epidemiology
- Genetics
Background:
- Accurate strain differentiation is crucial for understanding Campylobacter epidemiology.
- Multilocus sequence typing (MLST) is a reproducible technique for Campylobacter subtyping.
- MLST can group isolates into genetically related clonal complexes and may indicate host association.
Purpose of the Study:
- To conduct the first continuous population-based survey using MLST for Campylobacter epidemiology.
- To investigate MLST's potential in resolving campylobacteriosis epidemiology questions.
- To identify variations in campylobacteriosis epidemiology between distinct populations.
Main Methods:
- Utilized Multilocus Sequence Typing (MLST) for strain differentiation and subtyping.
- Conducted a continuous population-based epidemiological survey.
- Analyzed genetic relatedness and clonal complexes of Campylobacter isolates.
Main Results:
- Demonstrated MLST's capability to identify epidemiological variations in campylobacteriosis.
- Showcased MLST's effectiveness in distinguishing between different populations.
- Described the distribution of key Campylobacter subtypes relevant to epidemiology.
Conclusions:
- MLST is a valuable tool for detailed Campylobacter epidemiology studies.
- Continuous population-based surveys with MLST can resolve epidemiological questions.
- MLST effectively reveals population-specific variations in campylobacteriosis.
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