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Updated: Jul 18, 2026

Utilizing the Antigen Capsid-Incorporation Strategy for the Development of Adenovirus Serotype 5-Vectored Vaccine Approaches
Published on: May 6, 2015
Chimpanzee adenovirus antibodies in humans, sub-Saharan Africa
Zhiquan Xiang1, Yan Li, Ann Cun
1The Wistar Institute, Philadelphia, Pennsylvania 19104, USA.
Abstract:
Human sera from the United States, Thailand, and sub-Saharan Africa and chimpanzee sera were tested for neutralizing antibodies to 3 chimpanzee adenoviruses. Antibodies were more common in humans residing in sub-Saharan Africa than in humans living in the United States or Thailand. This finding suggests cross-species transmission of chimpanzee adenoviruses.
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