Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jul 18, 2026

Laparoscopic Anatomical Liver Segment VII Resection with Liver Parenchymal Transection Following a Priority Approach
13:57

Laparoscopic Anatomical Liver Segment VII Resection with Liver Parenchymal Transection Following a Priority Approach

Published on: May 23, 2025

[Acute liver failure--surgical approach].

S Jonas1

  • 1Klinik für Allgemein-,Viszeral- und Transplantationschirurgie, Charité Campus Virchow-Klinikum, Universitätsmedizin Berlin. sven.jonas@charite.de

Praxis
|December 21, 2006
PubMed
Summary

Emergency liver transplantation offers proven benefit for acute liver failure patients. While prognostic scores have limitations, key factors like multi-organ failure and encephalopathy guide decisions for this life-saving procedure.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Invasive cardiac aspergillosis after orthotopic liver transplantation.

Zeitschrift fur Gastroenterologie·2014
Same author

Management of urologic complications in renal transplantation: a single-center experience.

Transplantation proceedings·2014
Same author

Mid- and long-term results after replacement of infected peripheral vascular prosthetic grafts with biosynthetic collagen prosthesis.

The Journal of cardiovascular surgery·2014
Same author

[Use of radioactive iodine in the treatment of hyperthyroidism].

Primena radioaktivnih izotopa i jonizujucih zracenja u medicini; bilten·2014
Same author

Isolation and hepatocyte differentiation of mesenchymal stem cells from porcine bone marrow--"surgical waste" as a novel MSC source.

Transplantation proceedings·2013
Same author

Gender differences in intimate partner violence and psychiatric disorders in England: results from the 2007 adult psychiatric morbidity survey.

Epidemiology and psychiatric sciences·2013

Area of Science:

  • Hepatology
  • Transplantation Medicine
  • Critical Care Medicine

Context:

  • Acute liver failure (ALF) necessitates timely intervention.
  • Liver transplantation is the sole curative option for ALF.
  • Current decision-making for transplantation relies heavily on clinical expertise.

Purpose:

  • To evaluate the efficacy and outcomes of emergency liver transplantation in ALF.
  • To identify critical prognostic factors influencing transplantation decisions and patient survival.
  • To compare outcomes of ALF transplantation with those for chronic liver disease.

Summary:

  • Emergency liver transplantation is the primary treatment for acute liver failure.
  • Prognostic scoring systems show reliable positive predictive value but limited negative predictive value (60%).
  • Key predictors of outcome include multi-organ failure severity and pre-transplant encephalopathy grade.

Impact:

  • Despite a 20-30% postoperative mortality, long-term survival after successful ALF transplantation is generally excellent.
  • Improved prognostic accuracy could optimize patient selection and resource allocation.
  • This highlights the critical role of transplantation in managing life-threatening liver conditions.

More Related Videos

Laparoscopic Anatomical Right Hemihepatectomy via the In Situ Anterior Approach
05:30

Laparoscopic Anatomical Right Hemihepatectomy via the In Situ Anterior Approach

Published on: August 8, 2025

Related Experiment Videos

Last Updated: Jul 18, 2026

Laparoscopic Anatomical Liver Segment VII Resection with Liver Parenchymal Transection Following a Priority Approach
13:57

Laparoscopic Anatomical Liver Segment VII Resection with Liver Parenchymal Transection Following a Priority Approach

Published on: May 23, 2025

Laparoscopic Anatomical Right Hemihepatectomy via the In Situ Anterior Approach
05:30

Laparoscopic Anatomical Right Hemihepatectomy via the In Situ Anterior Approach

Published on: August 8, 2025