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[Therapy and anthelmintic resistance].

C Genchi1

  • 1Department of Animal Pathology, Hygiene and Veterinary Public Health, Section of General Pathology and Parasitology, University of Milan, Italy. claudio.genchi@unimi.it

Parassitologia
|December 21, 2006
PubMed
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Effective nematode parasite control in sheep and goats requires integrated strategies. This review covers anthelmintic drug classes, resistance, and alternative methods for sustainable livestock health.

Area of Science:

  • Veterinary Parasitology
  • Animal Science
  • Pharmacology

Context:

  • Nematode parasite infections pose significant risks to sheep and goat health and productivity.
  • Understanding risk factors is crucial for effective parasite control programs.
  • Modern anthelmintics target nematode parasites through various chemical mechanisms.

Purpose:

  • To review current treatments for nematode parasites in sheep and goats.
  • To discuss the mechanisms of action of major anthelmintic drug classes.
  • To highlight the importance of integrated control strategies and alternative measures.

Summary:

  • This review examines nematode parasite control in sheep and goats, outlining risk factors and detailing the mechanisms of action for key anthelmintic drug classes (imidazothiazoles, pyrimidines, benzimidazoles, macrocyclic lactones).

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  • It emphasizes the potential for anthelmintic resistance and advocates for strategic, integrated control plans considering herd epidemiology, composition, production, and drug efficacy.
  • The role of diet and alternative control methods, including nematophagous fungi and natural compounds like tannins, are also discussed.

    • Impact:

    • Provides a comprehensive overview of anthelmintic treatments and resistance in small ruminants.
    • Informs the development of sustainable parasite management strategies.
    • Highlights the need for a holistic approach combining chemical, biological, and nutritional interventions for optimal herd health and productivity.