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Updated: Jul 18, 2026

Three-Dimensional Bone Extracellular Matrix Model for Osteosarcoma
Published on: April 12, 2019
Spontaneous regression of osteochondromas
Manabu Hoshi1, Masatsugu Takami, Ryouji Hashimoto
1Department of Orthopaedic Surgery, Yodogawa Christian Hospital, 2-9-26 Awaji, Higashi-Yodogawa-Ku, Osaka, 533-0032, Japan. hoshi@med.osaka-cu.ac.jp
Abstract:
Spontaneous regression of an osteochondroma is an infrequent event. In this report, two cases with spontaneous regression of osteochondromas are presented. The first case was a solitary osteochondroma of the pedunculated type involving the right proximal humerus in a 7-year-old boy. This lesion resolved over 15 months of observation. The second case was a 3-year-old girl with multiple osteochondromatosis, in whom sessile osteochondromas of the right tibia and left fibula regressed over 33 months. The mechanism of this phenomenon is discussed with a review of previous reports. Regarding treatment, careful observation may be acceptable for typical osteochondromas, especially in young children.
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