Related Experiment Video
Updated: Jul 18, 2026

Murine Model for Non-invasive Imaging to Detect and Monitor Ovarian Cancer Recurrence
Published on: November 2, 2014
Spontaneous regression in recurrent epithelial ovarian cancer
Ritsuto Fujiwaki1, Kohji Sawada
1Department of Obstetrics and Gynecology, Matsue Red Cross Hospital, Horo 200, Matsue 690-0886, Japan. fuji39@circus.ocn.ne.jp
Background:
Although spontaneous regression has been reported in several cancers, it is generally believed that this rare phenomenon does not occur in epithelial ovarian cancer.
Case:
We presented a stage IV epithelial ovarian cancer patient with long-term disease-free survival after palliative local irradiation alone against recurrence. The recurrent supraclavicular lymph node was almost completely necrotic, and the swelling of the para-aortic lymph node spontaneously regressed.
Conclusion:
The histologic features and unexpected clinical course in this patient strongly suggest that spontaneous regression occurred in recurrent epithelial ovarian cancer.
Related Concept Videos
Oogenesis
The Retinoblastoma Gene
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...
Ovarian Cycle

