Related Experiment Video
Updated: May 5, 2026

07:59
Bioluminescence Imaging to Detect Late Stage Infection of African Trypanosomiasis
Published on: May 18, 2016
7.2K
Blinding trachoma in postconflict southern Sudan
Jeremiah Ngondi1, Francis Ole-Sempele, Alice Onsarigo
1Department of Public Health and Primary Care, Institute of Public Health, University of Cambridge, Cambridge, United Kingdom. jn250@cam.ac.uk
Plos Medicine
|December 21, 2006
Summary
Trachoma is a significant public health issue in southern Sudan, with high rates of active infection and trichiasis. Urgent implementation of the SAFE strategy is needed for trachoma control in Mankien.
Area of Science:
- Ophthalmology
- Public Health
- Infectious Diseases
Background:
- Trachoma is a leading cause of preventable blindness globally.
- Anecdotal evidence suggested a high burden of blinding trachoma in Mankien payam, southern Sudan.
- Previous data on trachoma prevalence in the region were limited.
Purpose of the Study:
- To estimate the prevalence of trachoma in Mankien payam.
- To determine targets for trachoma interventions.
- To establish a baseline for monitoring and evaluation of control programs.
Main Methods:
- A population-based cross-sectional survey was conducted in May 2005.
- Two-stage cluster random sampling with probability proportional to size was employed.
- Experienced graders used the World Health Organization simplified grading scheme for diagnosis.
Main Results:
- Active trachoma (TF or TI) prevalence in children aged 1-9 years was 63.3%.
- Trachomatous trichiasis prevalence was 9.6% overall, and 19.2% in adults.
- An estimated 5,344 individuals in Mankien payam require trichiasis surgery.
Conclusions:
- Trachoma poses a serious public health threat in Mankien.
- High prevalence of trichiasis, even in children, highlights the severity of the disease.
- The SAFE (Surgery, Antibiotics, Facial cleanliness, Environmental change) strategy should be urgently implemented for trachoma control.
Related Concept Videos
Angle Closure Glaucoma: Treatment
1.6K
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
1.6K
Sexually Transmitted Infections
2.0K
Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
2.0K

