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Updated: Jul 18, 2026

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Published on: January 10, 2025
The functions of RPS19 and their relationship to Diamond-Blackfan anemia: a review
Kenji Morimoto1, Shou Lin, Kathleen Sakamoto
1Division of Hematology/Oncology, Department of Pediatrics, UCLA Mattel Children's Hospital, CA 90095, USA. kmorimoto@mednet.ucla.edu
Abstract:
The relatively new study of ribosomal proteins has allowed for greater understanding of protein synthesis; however the connection between ribosomal proteins' roles and that of disease pathophysiology has not yet been established. RPS19 is a ribosomal protein linked to Diamond-Blackfan anemia whose functions have begun to be elucidated. We review here the known roles of RPS19 in both ribosome construction and other extra-ribosomal functions and discuss their relationship to Diamond-Blackfan anemia.
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