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Related Experiment Video

Updated: Jul 18, 2026

Modified Laparoscopic Anatomic Hepatectomy: Two-Surgeon Technique Combined with the Simple Extracorporeal Pringle Maneuver
12:27

Modified Laparoscopic Anatomic Hepatectomy: Two-Surgeon Technique Combined with the Simple Extracorporeal Pringle Maneuver

Published on: June 16, 2023

New techniques of liver surgery.

Kenneth K Tanabe1

  • 1Massachusetts General Hospital, Boston, MA 02114, USA.

Seminars in Oncology
|December 21, 2006
PubMed
Summary

Liver resection for colorectal cancer metastases is advancing, expanding patient eligibility and improving long-term survival. New strategies convert non-resectable tumors to resectable ones, enhancing outcomes.

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The CD49b (ITGA2) collagen receptor excludes CD8<sup>+</sup> T cell infiltration in pancreatic ductal adenocarcinoma.

iScience·2026
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Single-cell transcriptomics reveals the impact of sex and age in the healthy human liver.

JHEP reports : innovation in hepatology·2026
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Neoadjuvant stereotactic body radiation therapy plus immune therapy favorably remodels the hepatocellular carcinoma tumor microenvironment.

Clinical cancer research : an official journal of the American Association for Cancer Research·2026
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Correction: Improving the therapeutic efficacy of sorafenib for hepatocellular carcinoma by repurposing disulfiram.

Frontiers in oncology·2026
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High-speed wide-field fluorescence lifetime imaging for intraoperative tumor visualization and in vivo multiplexing.

Biomedical optics express·2025
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<sup>18</sup>F-FPP-RGD<sub>2</sub> PET Imaging for Interrogating Target Engagement and Antifibrotic Activity of an Integrin Antagonist in a Mouse Model of Metabolic Dysfunction-Associated Steatohepatitis.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine·2025

Area of Science:

  • Hepatobiliary Surgery
  • Surgical Oncology
  • Colorectal Cancer Treatment

Background:

  • Liver resection for colorectal cancer (CRC) metastases is a cornerstone treatment.
  • Traditional contraindications previously limited patient selection for this procedure.

Purpose of the Study:

  • To review the evolving techniques and patient selection criteria for liver resection in CRC metastases.
  • To highlight advancements in surgical strategies and neoadjuvant therapies.

Main Methods:

  • Review of current literature on liver resection for CRC metastases.
  • Analysis of improvements in imaging, surgical techniques, and adjuvant therapies.
  • Evaluation of outcomes in patients with previously unresectable disease.

Main Results:

  • Surgical techniques and perioperative management have significantly improved.
  • Enhanced imaging and neoadjuvant therapies can convert unresectable disease to resectable.
  • Long-term survival is increasingly observed in a broader patient population.

Conclusions:

  • Liver resection for CRC metastases is becoming more feasible for a wider range of patients.
  • Advancements in surgical strategies and multimodal treatment are improving outcomes.
  • Continued research into novel techniques will further enhance survival rates.

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