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Updated: Jul 18, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
Management of atrial fibrillation
Timothy Watson1, Gregory Y H Lip
1University Department of Medicine, City Hospital, Birmingham, UK.
Insights
Atrial fibrillation (AF) is a growing epidemic. Effective antithrombotic therapy is crucial for managing AF patients and reducing stroke risk, regardless of treatment strategy.
Area of Science:
- Cardiology
- Internal Medicine
Background:
- Atrial fibrillation (AF) is the most prevalent cardiac arrhythmia in the European Union, impacting an estimated 4.5 million individuals.
- The incidence of AF is increasing due to an aging population and improved survival rates after heart attacks, leading to its characterization as a new epidemic.
Observation:
- Management of AF, whether through rate or rhythm control, necessitates appropriate antithrombotic therapy.
- Antithrombotic therapy is essential for mitigating the risks of stroke and thromboembolism in AF patients.
Findings:
- This overview synthesizes recently published guidelines on AF management.
- It provides practical applications of these guidelines through three clinical case scenarios.
Implications:
- The findings offer valuable insights for clinicians managing atrial fibrillation.
- Implementing guideline-recommended antithrombotic strategies can significantly improve patient outcomes by reducing thromboembolic events.
Abstract:
Atrial fibrillation (AF) is the most common cardiac arrhythmia, affecting an estimated 4.5 million people within the European Union. Indeed, the prevalence of AF continues to rise, in view of the aging population and the better management of heart attacks, making it the new "epidemic". Irrespective of a rate control or rhythm control strategy, appropriate antithrombotic therapy is central to AF management, by reducing the risk of stroke and thromboembolism. This overview focuses on the management of AF, with reference to recently published guidelines and describes their application in clinical practice using three clinical case scenarios.
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