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cDNA cloning of a novel testis-specific calcineurin B-like protein
1Department of Pharmacology, Kobe University School of Medicine, Japan.
Biochemical and Biophysical Research Communications
|September 30, 1991
Abstract:
A cDNA clone encoding a novel calcineurin B-like protein (CBLP) was isolated from a rat testis cDNA library by cross-hybridization with a calcineurin B cDNA probe. CBLP is composed of 176 amino acids and contains four putative Ca(2+)-binding domains. The overall predicted amino acid sequence homology between CBLP and calcineurin B is 82%. Northern blots showed that transcripts for CBLP are specifically and highly expressed in the testis.

