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Updated: Jul 18, 2026
09:34
Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease
Published on: April 4, 2018
Genomics and public health at CDC
Marta Gwinn1, M Bowen, M Khoury
1National Office of Public Health Genomics, CDC, 4770 Buford Hwy., MS K-89, Atlanta, GA 30342, USA. mgwinn@cdc.gov
MMWR Supplements
|December 22, 2006
Summary
Genomics advances public health by enabling rapid pathogen identification and tracking. New genomic tools help diagnose infections, identify virus origins, and detect mutations for better disease control.
Area of Science:
- Genomics and Public Health
- Infectious Disease Surveillance
Background:
- Genomics studies the entire genome and its interactions.
- Public health genomics includes genetic variation in human and microbial populations.
- Molecular typing of pathogens is crucial for infectious disease control.
Observation:
- Genomic research offers powerful new tools for public health.
- A new microchip-based method can diagnose influenza rapidly.
- This method distinguishes between human and animal virus origins.
Findings:
- The microchip-based method detects mutations suggesting increased virulence.
- It provides diagnostic results within hours.
- Genomic tools enhance infectious disease surveillance and response.
Implications:
- Genomic advancements improve epidemic tracing and vaccine development.
- Rapid diagnostics aid in controlling infectious disease outbreaks.
- Monitoring drug resistance and virulence mutations is enhanced.
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