Related Experiment Video
Updated: Jul 18, 2026

Minimally Invasive Murine Laryngoscopy for Close-Up Imaging of Laryngeal Motion During Breathing and Swallowing
Published on: December 1, 2023
Can objective parameters derived from videofluoroscopic assessment of post-laryngectomy valved speech replace current
R Kazi1, A Singh, G P J Mullan
1Head and Neck Unit, Royal Marsden Hospital, The Institute of Cancer Research, London, UK. rehan.kazi@rmh.nhs.uk
Objectives:
The primary purpose of this study was to assess the pharyngoesophageal segment in total laryngectomy patients using a videofluoroscopy e-tool.
Study Design:
Cross-sectional study.
Setting:
Head and Neck Oncology Unit, Tertiary Referral Centre.
Patients:
Forty-two patients following total laryngectomy.
Intervention:
Videofluoroscopy using an e-tool (JRuler).
Main Outcome Measures:
Subjective and objective videofluoroscopy parameters correlated with the GRBAS scale and treatment variables.
Results:
Of 32 men and 10 women, mean age 63.5 years (10.8) the majority (64.3%) had a reasonable voice (good = 11 and poor = 4 patients). Comparing subjective and objective parameters, significant correlations were only seen with a smaller minimal neoglottic distance at phonation with no regurgitation of barium at phonation (P = 0.05) and a type 1 shape of neoglottis at phonation (P = 0.02). There were also significant correlations between smaller maximum sub-neoglottic distance at phonation and type 1 shape of neoglottis (P = 0.02), smaller maximum sub-neoglottic distance at rest and absence of stasis of barium at phonation (P = 0.05) and the length of neoglottis at phonation and type 1 shape of neoglottis (P = 0.01). For perceptual evaluation, significant correlation was seen only between G1 voice and a smaller minimal neoglottic distance at phonation (P = 0.03) amongst the subjective and objective parameters. There were no correlations between visual parameters and the clinical parameters.
Conclusions:
Our observations suggest that this interesting concept has limitations. While objective and quantifiable data can be obtained using videofluoroscopy in laryngectomees, only a few correlate with each other and with voice quality.

