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Updated: Jul 18, 2026

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Orthotopic Implantation and Peripheral Immune Cell Monitoring in the II-45 Syngeneic Rat Mesothelioma Model
Published on: October 2, 2015
Prolonged survival due to spontaneous regression and surgical excision of malignant mesothelioma
John E Pilling1, Andrew G Nicholson, Clive Harmer
1Department of Thoracic Surgery, Royal Brompton Hospital, London, United Kingdom.
The Annals of Thoracic Surgery
|December 23, 2006
Abstract:
We report a case of malignant pleural mesothelioma with histologically proven spontaneous regression of pleural disease. During a 12-year follow-up there was a single recurrence, which was a lesion in the chest wall at 6 years that was surgically excised. A prominent host response to tumor was seen in both the primary tumor and the recurrence.

