Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Types of Toxins01:36

Types of Toxins

Humans continually engage with an environment rich in potentially harmful chemicals. These are introduced to our bodies through inhalation, ingestion, or skin contact. These chemicals exist in various forms, such as air and environmental pollutants, agricultural chemicals, organic solvents, and heavy metals.
Air pollutants, primarily gases, pose significant threats to respiratory health, leading to conditions like hypoxia, lung cancer, and in extreme cases, death.
Environmental pollutants like...
The Periodic Table and Organismal Elements01:27

The Periodic Table and Organismal Elements

Elements are the smallest units of matter that cannot be broken down further by chemical processes. There are 118 known elements, but not all of these are naturally occurring, and only a few of them are essential for life. Living matter is composed primarily of carbon, nitrogen, hydrogen, and oxygen, with smaller amounts of other elements like calcium, phosphorus, potassium, and sulfur. Other elements are also necessary for life but only in trace amounts.
Periodic Table Provides Information...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Towards replacement of animal tests with in vitro assays: a gene expression biomarker predicts in vitro and in vivo estrogen receptor activity.

Chemico-biological interactions·2022
Same author

A value of information framework for assessing the trade-offs associated with uncertainty, duration, and cost of chemical toxicity testing.

Risk analysis : an official publication of the Society for Risk Analysis·2022
Same author

Integrating publicly available information to screen potential candidates for chemical prioritization under the Toxic Substances Control Act: A proof of concept case study using genotoxicity and carcinogenicity.

Computational toxicology (Amsterdam, Netherlands)·2022
Same author

Evaluation of Existing QSAR Models and Structural Alerts and Development of New Ensemble Models for Genotoxicity Using a Newly Compiled Experimental Dataset.

Computational toxicology (Amsterdam, Netherlands)·2021
Same author

A Framework that Considers the Impacts of Time, Cost, and Uncertainty in the Determination of the Cost Effectiveness of Toxicity-Testing Methodologies.

Risk analysis : an official publication of the Society for Risk Analysis·2021
Same author

Utility of In Vitro Bioactivity as a Lower Bound Estimate of In Vivo Adverse Effect Levels and in Risk-Based Prioritization.

Toxicological sciences : an official journal of the Society of Toxicology·2019

Related Experiment Video

Updated: Jul 18, 2026

Demonstration of the DNA Fiber Assay for Investigating DNA Damage and Repair Dynamics Induced by Nanoparticles
13:09

Demonstration of the DNA Fiber Assay for Investigating DNA Damage and Repair Dynamics Induced by Nanoparticles

Published on: March 3, 2023

Nanoparticles: health effects--pros and cons.

Maureen R Gwinn1, Val Vallyathan

  • 1National Institute for Occupational Safety and Health, Morgantown, West Virginia 26505, USA.

Environmental Health Perspectives
|December 23, 2006
PubMed
Summary

Engineered nanoparticles (NPs) offer vast potential but pose unknown health risks. Precautionary measures are essential due to potential toxicological effects similar to ultrafine particles (UFPs).

Area of Science:

  • Nanotechnology
  • Materials Science
  • Toxicology

Background:

  • Nanotechnology enables engineered nanoparticles (<100 nm) for diverse applications like medicine and industry.
  • Potential toxic health effects of nanoparticles (NPs) on humans remain largely unknown.
  • Engineered NPs may share toxicological properties with ultrafine particles (UFPs) from anthropogenic sources.

Purpose of the Study:

  • To review potential toxic human health effects from exposure to engineered NPs.
  • To highlight cardiopulmonary outcomes associated with ultrafine particle (UFP) exposure.
  • To emphasize the need for precautionary measures due to knowledge gaps in NP toxicology.

Main Methods:

  • Review of existing literature on nanoparticle (NP) and ultrafine particle (UFP) toxicology.

More Related Videos

Experimental Protocol to Investigate Particle Aerosolization of a Product Under Abrasion and Under Environmental Weathering
07:47

Experimental Protocol to Investigate Particle Aerosolization of a Product Under Abrasion and Under Environmental Weathering

Published on: September 16, 2016

Ameliorating Osteoarthritis in Mice Using Silver Nanoparticles
05:50

Ameliorating Osteoarthritis in Mice Using Silver Nanoparticles

Published on: June 2, 2023

Related Experiment Videos

Last Updated: Jul 18, 2026

Demonstration of the DNA Fiber Assay for Investigating DNA Damage and Repair Dynamics Induced by Nanoparticles
13:09

Demonstration of the DNA Fiber Assay for Investigating DNA Damage and Repair Dynamics Induced by Nanoparticles

Published on: March 3, 2023

Experimental Protocol to Investigate Particle Aerosolization of a Product Under Abrasion and Under Environmental Weathering
07:47

Experimental Protocol to Investigate Particle Aerosolization of a Product Under Abrasion and Under Environmental Weathering

Published on: September 16, 2016

Ameliorating Osteoarthritis in Mice Using Silver Nanoparticles
05:50

Ameliorating Osteoarthritis in Mice Using Silver Nanoparticles

Published on: June 2, 2023

  • Comparative analysis of potential health effects based on particle size and properties.
  • Identification of research gaps concerning human exposure to engineered NPs.

    • Main Results:

    • Engineered NPs may exhibit unique toxic biological effects due to altered surface properties.
    • Ultrafine particles (UFPs) can be transported to distant sites, causing adverse health effects.
    • Potential for unintentional human exposure exists through beneficial NP applications.

    Conclusions:

    • Given the unknown health effects, a precautionary approach to NP use is ethically mandated.
    • Elucidating the toxicological effects of NPs is crucial for minimizing occupational and environmental exposure.
    • Understanding NP health risks is vital despite their technological and therapeutic benefits.