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[Posttraumatic meningitis: incidence, bacteriology, and outcomes]

H Kallel1, H Chelly, M Ghorbel

  • 1Service de Réanimation Médicale, CHU Habib-Bourguiba, route El-Aïn, km 1, 3029 Sfax, Tunisie. Kallelhat@yahoo.fr

Neuro-Chirurgie
|December 23, 2006
PubMed
Abstract

Insights

Antibiotic prophylaxis in head trauma patients may promote multidrug-resistant bacteria, increasing post-traumatic meningitis (PTM) risk. Key mortality predictors include Glasgow Coma Scale score and specific bacterial agents.

Area of Science:

  • Neuroscience
  • Infectious Diseases
  • Critical Care Medicine

Context:

  • Post-traumatic meningitis (PTM) is a serious complication following head injuries.
  • Understanding the incidence, causative organisms, and mortality factors of PTM is crucial for effective management.

Purpose:

  • To investigate the incidence, responsible organisms, and mortality predictors of post-traumatic meningitis (PTM).

Summary:

  • A retrospective study over seven years identified 38 PTM cases (0.96% of head injury admissions).
  • Multidrug-resistant Acinetobacter baumannii, Klebsiella pneumoniae, and Streptococcus pneumoniae were common pathogens.
  • Predictors of 14-day mortality included Glasgow Coma Scale (GCS) score, absence of nuchal rigidity, cerebrospinal fluid (CSF) protein, CSF/blood glucose ratio, and S. pneumoniae infection.

Impact:

  • Findings suggest avoiding antibiotic prophylaxis in head trauma to prevent multidrug-resistant bacteria emergence.
  • Identified prognostic factors (GCS, CSF protein, CSF/blood glucose ratio, S. pneumoniae) can guide clinical decision-making and patient care.

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