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Updated: Jul 18, 2026

The Use of Reverse Phase Protein Arrays (RPPA) to Explore Protein Expression Variation within Individual Renal Cell Cancers
Published on: January 22, 2013
[Paraneoplastic syndrome in renal cell carcinoma]
1Urologische Universitätsklinik, Ruprecht-Karls-Universität, 69120, Im Neuenheimer Feld 110, Heidelberg, Deutschland. jens.bedke@med.uni-heidelberg.de
Abstract:
Renal cell carcinoma associated paraneoplastic symptoms include constitutional symptoms as well as specific metabolic and biochemical abnormalities. These are present in up to 40% of patients with renal cell carcinoma during the course of the disease. This report provides information on the most common manifestations and their therapy; some rare variants are also mentioned. The importance of paraneoplasia lies partly in the fact that paraneoplastic symptoms may be the precursor of either primary or recurrent disease. The presence of paraneoplastic manifestations does not necessarily imply a poor prognosis or metastatic disease.
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