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Updated: Jul 18, 2026

A Syngeneic Mouse Model of Metastatic Renal Cell Carcinoma for Quantitative and Longitudinal Assessment of Preclinical Therapies
Published on: April 12, 2017
[Brain metastases in cases of renal cell carcinoma]
1Urologische Universitätsklinik, Ruprecht-Karls-Universität, 69121, Im Neuenheimer Feld 110, Heidelberg, Deutschland. stephan.buse@med.uni-heidelberg.de
Abstract:
Brain metastases represent the most common intracranial neoplasia. The lung, breast and kidney are the primary tumor locations most often associated with brain metastasis. Seizures and neurological impairment are typical manifestations of neoplastic cerebral dissemination, which, when untreated, usually lead to death within a few months. In this review, we discuss whole brain radiotherapy, surgical resection and stereotactic radiosurgery as the currently used therapeutic options for renal cell cancer metastasis in the brain.
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