Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Anastomoses01:19

Anastomoses

In human anatomy, anastomosis refers to a connection or opening between two things, particularly between blood vessels or other tubular structures. The term is derived from the Greek term 'anastomosis,' which means 'outlet' or 'opening.' This natural network of connections plays a critical role in the survival and functionality of the human body.
Anastomoses can be formed at arterial, venous, and lymphatic vessels.
Arterial Anastomosis: These occur between arteries. They are most common in...
Fetal Circulation01:14

Fetal Circulation

Fetal circulation is a unique system that facilitates the exchange of gases, nutrients, and waste products between the developing fetus and the mother. This intricate process takes place through a special organ called the placenta.
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...
Abdominal Aorta01:25

Abdominal Aorta

Once the aorta traverses the diaphragmatic plane at the aortic hiatus, it is known as the abdominal aorta. This anatomical structure is positioned leftward of the spinal column, encased within a cocoon of adipose tissue behind the peritoneal cavity. It terminates at the L4 vertebra, where it splits into the common iliac arteries. Prior to this bifurcation, the abdominal aorta gives rise to several vital branches.
The celiac trunk, a singular artery, divides into the left gastric artery, which...
Development of Blood Vessels01:07

Development of Blood Vessels

The development of the vascular system in a fetus is a complex and intricate process that begins as early as 15 to 16 days post-conception. This process starts outside the embryo, specifically in the mesoderm of the yolk sac, chorion, and connecting stalk. Approximately two days later, the formation of blood vessels occurs within the embryo itself.
The initial formation of this system is facilitated by the small amount of yolk present in the ovum and yolk sac. Blood vessels originate from...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Blood loss due to diagnostic testing in extremely preterm infants in 22 European countries: a prospective observational study.

EClinicalMedicine·2026
Same author

The role of placental anastomoses in severe brain injury after fetal demise in monochorionic twins: a multicenter retrospective study.

American journal of obstetrics and gynecology·2026
Same author

Insights in fetal growth trajectories of spontaneous twin anemia polycythemia sequence twins.

Fetal diagnosis and therapy·2026
Same author

Early Prediction Model for Retinopathy of Prematurity Using Placental and Neonatal Risk Factors.

Investigative ophthalmology & visual science·2026
Same author

Peripheral blood cell counts of prematurely born, small for gestational age neonates.

Clinical and experimental pediatrics·2026
Same author

Alloimmunisation in pregnancy: current management and future perspectives.

Best practice & research. Clinical obstetrics & gynaecology·2026

Related Experiment Video

Updated: Jul 18, 2026

Accurate and Simple Evaluation of Vascular Anastomoses in Monochorionic Placenta using Colored Dye
09:52

Accurate and Simple Evaluation of Vascular Anastomoses in Monochorionic Placenta using Colored Dye

Published on: September 5, 2011

Deep-hidden anastomoses in monochorionic twin placentae are harmless.

Jeroen P H M van den Wijngaard1, Enrico Lopriore, Sandra M A van der Salm

  • 1Laser Center, Academic Medical Center, University of Amsterdam, The Netherlands. j.p.vandenwijngaard@amc.uva.nl

Prenatal Diagnosis
|December 23, 2006
PubMed
Summary

Deep-hidden anastomoses, placental vascular connections beneath the placental surface, do not appear to cause significant clinical consequences. Studies indicate these anastomoses do not lead to increased inter-twin hemoglobin differences in either twin-twin transfusion syndrome or control cases.

More Related Videos

Guide Wire Assisted Catheterization and Colored Dye Injection for Vascular Mapping of Monochorionic Twin Placentas
09:04

Guide Wire Assisted Catheterization and Colored Dye Injection for Vascular Mapping of Monochorionic Twin Placentas

Published on: September 5, 2011

Related Experiment Videos

Last Updated: Jul 18, 2026

Accurate and Simple Evaluation of Vascular Anastomoses in Monochorionic Placenta using Colored Dye
09:52

Accurate and Simple Evaluation of Vascular Anastomoses in Monochorionic Placenta using Colored Dye

Published on: September 5, 2011

Guide Wire Assisted Catheterization and Colored Dye Injection for Vascular Mapping of Monochorionic Twin Placentas
09:04

Guide Wire Assisted Catheterization and Colored Dye Injection for Vascular Mapping of Monochorionic Twin Placentas

Published on: September 5, 2011

Area of Science:

  • Perinatology
  • Fetal Medicine
  • Obstetrics

Background:

  • Deep-hidden anastomoses are vascular connections located beneath the placental surface.
  • These anastomoses have been implicated in various placental pathologies, including twin-twin transfusion syndrome (TTTS).
  • Understanding their clinical significance is crucial for accurate diagnosis and management.

Purpose of the Study:

  • To investigate the clinical consequences of deep-hidden anastomoses.
  • To determine if deep-hidden anastomoses contribute to inter-twin hemoglobin differences.
  • To assess the impact of these anastomoses in both TTTS and non-TTTS pregnancies.

Main Methods:

  • Analysis of 12 placentae from TTTS cases treated with intrauterine laser ablation and 14 non-TTTS control placentae.
  • Investigation for the presence of deep-hidden anastomoses.
  • Measurement of inter-twin hemoglobin differences as a marker of fetofetal transfusion.

Main Results:

  • Deep-hidden anastomoses were found in 58% of TTTS placentae and 64% of non-TTTS placentae.
  • No significant difference in inter-twin hemoglobin levels was observed between TTTS placentae with and without deep-hidden anastomoses (medians 1.4 vs 1.2 gr/dL).
  • In non-TTTS placentae, deep-hidden anastomoses did not significantly increase inter-twin hemoglobin differences (medians 2.6 vs 5.1 gr/dL).

Conclusions:

  • Deep-hidden anastomoses do not appear to cause additional increases in hemoglobin difference.
  • Hematological and hemodynamic analyses suggest that deep-hidden anastomoses likely occur without clinical consequences.
  • These findings indicate that deep-hidden anastomoses may be a common finding with minimal clinical impact.