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Updated: Jul 18, 2026

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Published on: June 2, 2014
[Ophthalmoplegic migraine: case report]
Paulo Hélio Monzillo1, Victor Marçal Saab, Gustavo Guimarães Protti
1Disciplina de Neurologia, Santa Casa de Misericórdia de São Paulo, São Paulo, SP, Brasil. monzillo@einstein.br
Ophthalmoplegic migraine, a rare disorder causing headaches and eye muscle paralysis, presents unique challenges. This case highlights unusual symptoms and the importance of differential diagnosis for this condition.
Area of Science:
- Neurology
- Ophthalmology
Background:
- Ophthalmoplegic migraine is a rare neurological disorder characterized by recurrent headaches and temporary paralysis of eye muscles.
- The underlying pathophysiology of ophthalmoplegic migraine remains poorly understood, necessitating further research.
Observation:
- This report details an unusual case of ophthalmoplegic migraine diagnosed using International Headache Society criteria.
- The patient experienced their first episode in adulthood, with pain side variability and painless oculomotor abnormalities during the latest crisis.
Findings:
- The case presented atypical features, including adult-onset, shifting pain laterality, and painless ophthalmoplegia.
- Diagnosis relies on exclusion, underscoring the need for thorough differential diagnosis.
Implications:
- This case emphasizes the variability in ophthalmoplegic migraine presentation.
- It highlights the critical need for comprehensive etiological investigation and differential diagnosis in managing patients with suspected ophthalmoplegic migraine.
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