Related Experiment Video

Updated: Jul 18, 2026

Establishment of a High-throughput Setup for Screening Small Molecules That Modulate c-di-GMP Signaling in Pseudomonas aeruginosa
11:31

Establishment of a High-throughput Setup for Screening Small Molecules That Modulate c-di-GMP Signaling in Pseudomonas aeruginosa

Published on: June 30, 2016

The bacterial second messenger cyclic diGMP exhibits potent adjuvant properties

Thomas Ebensen1, Kai Schulze, Peggy Riese

  • 1Department of Vaccinology, Helmholtz Centre for Infection Research, Inhoffenstrasse 7, 38124 Braunschweig, Germany.

Vaccine
|December 26, 2006
PubMed
Summary

Bis-(3',5')-cyclic dimeric guanosine monophosphate (cdiGMP) shows strong adjuvant properties. Co-administration with antigens significantly boosts immune responses, suggesting cdiGMP is a promising vaccine adjuvant.

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