When CDK1 rides the telomere cycle
M Teresa Teixeira1, Eric Gilson
1Laboratoire de Biologie Moléculaire de la Cellule of Ecole Normale Supérieure de Lyon, UMR CNRS/INRA/ENS, IFR 128 BioSciences Lyon Gerland, 46 Allée d'Italie, 69364 Lyon Cedex 07, France.
Abstract:
Reconstitution of telomeric DNA at each cell division implies the coordination of DNA semiconservative replication with several processing events still poorly understood. Two reports published recently in Molecular Cell show that a cell-cycle cyclin-dependent kinase, Cdk1p, is required to create the cell-cycle-regulated overhang ().
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