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Related Concept Videos

Appendicitis-II: Diagnostic Studies and Management01:29

Appendicitis-II: Diagnostic Studies and Management

Diagnosing and managing appendicitis requires a structured and comprehensive approach that spans from initial assessment to postoperative care. Here is an overview of the process:
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
Appendicitis-I: Introduction01:22

Appendicitis-I: Introduction

The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
Appendicitis01:19

Appendicitis

Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...
Psychosurgery01:30

Psychosurgery

Psychosurgery, the surgical alteration or permanent removal of brain tissue to alleviate severe psychological conditions, stands as one of the most radical and controversial treatments in the history of mental health care. Its development and application have evolved significantly, marked by dramatic shifts in scientific understanding and ethical perspectives.
Historical Development of Psychosurgery
In the 1930s, Portuguese neurologist Antonio Egas Moniz introduced a surgical procedure designed...
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy01:26

Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy

Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...

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Related Experiment Video

Updated: Jul 18, 2026

Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch
08:51

Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch

Published on: August 24, 2019

Appendectomy for appendicitis in patients with schizophrenia.

Brian K Cooke1, Louis T Magas, Katherine S Virgo

  • 1Department of Veterans Affairs Medical Center, St Louis, MO, USA.

American Journal of Surgery
|December 26, 2006
PubMed
Summary

Schizophrenia patients undergoing appendectomy face delayed diagnosis and high rates of complications and death. This study highlights critical areas for improved care in this vulnerable population.

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Area of Science:

  • Medical research
  • Clinical outcomes
  • Schizophrenia research

Background:

  • Anecdotal evidence suggests poor surgical outcomes for schizophrenia patients.
  • This study investigates the clinical course of schizophrenia patients with appendicitis undergoing appendectomy.

Purpose of the Study:

  • To determine the clinical course and outcomes of schizophrenia patients with appendicitis who underwent appendectomy.
  • To identify common preoperative risk factors and adverse outcomes.

Main Methods:

  • Utilized Department of Veterans Affairs national datasets (Patient Treatment File, Beneficiary Identification and Records Location System).
  • Identified patients with schizophrenia or schizoaffective disorder diagnosed with appendicitis (FY1995-1999).
  • Collected data on risk factors and 25 adverse outcomes, including mortality.

Main Results:

  • 55 patients identified (mean age 49, 96% male).
  • Appendicitis diagnosed late (median 3 days from onset); 66% had perforated appendix.
  • High complication rate (56%) and in-hospital mortality (4%).

Conclusions:

  • First report on appendicitis outcomes in schizophrenia patients.
  • Late diagnosis, frequent adverse behaviors, and high complication/mortality rates observed.
  • Highlights need for improved diagnostic and treatment strategies.