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Updated: Jul 18, 2026

Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting
Published on: May 1, 2015
Histopathologic abnormalities of the lymphoreticular tissues in organic cation transporter 2 deficiency: evidence for
Katalin Komlósi1, Viktória Havasi, Judit Bene
1Department of Medical Genetics and Child Development, University of Pécs, Pécs, Hungary.
Abstract:
Immunohistology of lymphoreticular tissues of a fatal case of organic cation transporter 2 deficiency revealed inhibited proliferation with increased apoptosis in the germinal centers, resulting in "burned out" follicles. This is indicative of impaired antigen driven B cell affinity maturation. Defective humoral immune response might explain the recurrent infections in untreated organic cation transporter 2 deficiency.
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