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Methods for the Isolation, Culture, and Functional Characterization of Sinoatrial Node Myocytes from Adult Mice
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TRPM4, a Ca2+-activated nonselective cation channel in mouse sino-atrial node cells

Marie Demion1, Patrick Bois, Pierre Launay

  • 1Institut de Physiologie et Biologie Cellulaires, CNRS UMR 6187, Université de Poitiers, F-86022 Poitiers Cedex, France.

Cardiovascular Research
|December 26, 2006
PubMed
Summary

Calcium-activated nonselective cation channels (NSC(Ca)), identified as TRPM4, are present in mouse sino-atrial node cells. This discovery suggests TRPM4 channels play a role in regulating heart rhythm.

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