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To die or not to die: a HAT trick
Sandrine Tyteca1, Gaëlle Legube, Didier Trouche
1LBME, CNRS and Université Paul Sabatier, 118 Route de Narbonne, 31062 Toulouse, France.
Molecular Cell
|December 26, 2006
Abstract:
In this issue of Molecular Cell, two manuscripts (Sykes et al., 2006) propose that the decision to undergo apoptosis upon DNA damage is mediated through acetylation of p53 within its DNA-binding domain by MYST histone acetyltransferases.
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